Permeability of Psoralen Derivatives in Lipid Membranes
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چکیده
منابع مشابه
Ionic Permeability of Thin Lipid Membranes
Ultrathin (black) lipid membranes were made from sheep red cell lipids dissolved in n-decane. The presence of aliphatic alcohols in the aqueous solutions bathing these membranes produced reversible changes in the ionic permeability, but not the osomotic permeability. Heptanol (8 mM), for example, caused the membrane resistance (R(m)) to decrease from >10(8) to about 10(5) ohm-cm(2) and caused a...
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The osmotic permeability coefficient, P(f), and the tagged water permeability coefficient, P(d), were determined for thin (<100 A) lipid membranes formed from ox brain lipids plus DL-alpha-tocopherol; their value of approximately 1 x 10(-3) cm/sec is within the range reported for plasma membranes. It was established that P(f) = P(d). Other reports that P(f) > P(d) can be attributed to the prese...
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In membranes containing aqueous pores (channels), the osmotic water permeability coefficient, P f, is greater than the diffusive water permeability coefficient, P d. In fact, the magnitude of P f/P d is commonly used to determine pore radius. Although, for membranes studied to date, P f/P d monotonically declines with decreasing pore radius, there is controversy over the value it theoretically ...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2006
ISSN: 0006-3495
DOI: 10.1529/biophysj.105.077156